(Semi-) automatic biochemistry analyzers are medical laboratory instruments, widely applied in hospitals and research institutes. They are designed for the quantitative determination of different biochemical substances and other characteristics in a number of biological samples. These measured properties of blood and other fluids may be useful in the diagnosis of disease. The type of in vitro diagnostic test that can be performed on this analyzer include enzyme levels (such as many of the liver function tests), ion levels (e.g. sodium and potassium), and other tell-tale chemicals (such as glucose, serum albumin, or creatinine). Enzymes may be measured by the rate they change one colored substance to another; in these tests, the results for enzymes are given as an activity, not as a concentration of the enzyme. Other tests use colorimetric changes to determine the concentration of the chemical in question. Turbidity may also be measured. The automation of laboratory testing does not remove the need for human expertise (results must still be evaluated by medical technologists and other qualified clinical laboratory professionals), but it does minimize the potential human errors, resulting in higher precision and accuracy. Furthermore, it reduces sample and reagent volumes and increases the speed of the testing compared to measurement with a spectrophotometer. NOTE: The CYANSmart is a system that allows configuration with different reagents selected by the customer in order to fit his needs. Upon delivery, the instrument is configured for the validated biochemistry kits of Cypress Diagnostics. In order to assure the analytical performances of the system “instrument + reagents”, we strongly recommend only to use reagents, controls and calibrators validated on the CYANSmart.